Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | F12 | P00748 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | C1S | P09871 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3058170 | 0.82 | ALDH1A1 (0.48) | ALDH1A1F2F10F12F7 | |
| SCHEMBL725723 | 0.78 | ALDH1A1 (0.36) | ALDH1A1F2F10F12F7 | |
| SCHEMBL1741633 | 0.78 | LMNA (0.44) | ALDH1A1KMT2AMEN1KDM4EPLAU | |
| SCHEMBL28899661 | 0.78 | ALDH1A1 (0.36) | ALDH1A1F2F10F12F7 | |
| SCHEMBL836169 | 0.77 | MEN1 (0.44) | ALDH1A1F2F10F12F7 | |
| Hydrochloric Acid SCHEMBL28340528 | 0.77 | LMNA (0.43) | ALDH1A1BLMKMT2AMEN1PRSS1 | |
| Hydrochloric Acid SCHEMBL7199219 | 0.77 | BLM (0.38) | ALDH1A1F2F10F12F7 | |
| SCHEMBL10448622 | 0.77 | MEN1 (0.44) | ALDH1A1F2F10F12F7 | |
| SCHEMBL16908930 | 0.77 | CRHBP (0.39) | ALDH1A1KMT2AMEN1NPC1NPSR1 | |
| SCHEMBL28899636 | 0.76 | MEN1 (0.42) | ALDH1A1F2F10F12F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115414480-A | Dianhydrogalactitol in combination with radiation for treatment of non-small cell lung cancer and glioblastoma multiforme | 德玛医药 | 2022-12-02 | — | — | CN | disclosed |