Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 14/20 | 0.50 |
| ▸ | THRB | P10828 | 14/20 | 0.50 |
| ▸ | EGLN1 | Q9GZT9 | 7/20 | 0.50 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.42 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | ASPH | Q12797 | 1/20 | 0.40 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29923141 | 1.00 | THRA (0.50) | THRATHRBEGLN1ERCC1FEN1 | |
| SCHEMBL28899887 | 0.88 | THRB (0.50) | THRATHRBEGLN1ERCC1FEN1 | |
| SCHEMBL14672082 | 0.83 | THRA (0.70) | THRATHRBEGLN1BBOX1SLC6A2 | |
| SCHEMBL28899786 | 0.76 | THRA (0.52) | THRATHRBEGLN1ERCC1FEN1 | |
| SCHEMBL28899951 | 0.75 | ALDH1A1 (0.56) | ERCC1FEN1ERCC4 | |
| SCHEMBL29922978 | 0.75 | ALDH1A1 (0.56) | ERCC1FEN1ERCC4 | |
| SCHEMBL28899800 | 0.74 | THRA (0.74) | THRATHRBEGLN1BBOX1SLC6A2 | |
| SCHEMBL2017928 | 0.74 | EGLN1 (0.58) | THRATHRBEGLN1ERCC1FEN1 | |
| Acetic Acid SCHEMBL28993798 | 0.73 | THRA (0.65) | THRATHRBEGLN1BBOX1SLC6A2 | |
| SCHEMBL8147532 | 0.71 | NPSR1 (0.42) | THRATHRBEGLN1ERCC1FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107382986-B | 4-hydroxy-1-methylisoquinoline derivatives and their use in increasing endogenous erythropoietin | 江苏艾立康医药科技有限公司 | 2022-09-20 | — | — | CN | disclosed |