Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 9/20 | 0.50 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29412023 | 1.00 | PARP1 (0.52) | PARP1PPARGTLR7HDAC1HDAC8 | |
| SCHEMBL29412078 | 0.89 | LMNA (0.55) | PARP1PPARG | |
| SCHEMBL28487665 | 0.81 | PKN1 (0.56) | PARP1HDAC1HDAC8 | |
| SCHEMBL29412017 | 0.81 | PKN1 (0.56) | PARP1HDAC1HDAC8 | |
| SCHEMBL28478408 | 0.77 | ALDH1A1 (0.58) | PARP1PPARG | |
| SCHEMBL29412060 | 0.77 | PKN1 (0.54) | PARP1PPARG | |
| SCHEMBL28494472 | 0.77 | PARP1 (0.49) | PARP1PPARGPOLB | |
| SCHEMBL28479697 | 0.77 | PPARG (0.50) | PARP1PPARG | |
| SCHEMBL29411973 | 0.77 | PPARG (0.50) | PARP1PPARG | |
| SCHEMBL6953212 | 0.77 | PPARG (0.50) | PARP1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111978301-B | Benzimidazole compound with endothelial lipase inhibition effect and application thereof | 盐城师范学院 | 2022-08-02 | — | — | CN | disclosed |
| CN-111978301-A | Benzimidazole compound with endothelial lipase inhibition effect and application thereof | 盐城师范学院 | 2020-11-24 | — | — | CN | disclosed |