Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.37 |
| ▸ | AHR | P35869 | 2/20 | 0.35 |
| ▸ | AKT2 | P31751 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18015431 | 0.79 | KDM4E (0.70) | KDM4EALDH1A1METTL3AHRCASP3 | |
| SCHEMBL23726440 | 0.77 | METTL3 (0.46) | KDM4EALDH1A1METTL3AHRLMNA | |
| SCHEMBL28903295 | 0.76 | KDM4E (0.47) | KDM4EALDH1A1AHRLMNAPOLB | |
| SCHEMBL23725727 | 0.76 | KDM4E (0.43) | KDM4EALDH1A1METTL3AHRLMNA | |
| SCHEMBL23414795 | 0.76 | ALDH1A1 (0.41) | KDM4EALDH1A1METTL3LMNAPOLB | |
| SCHEMBL18015437 | 0.74 | RAB9A (0.51) | KDM4EALDH1A1AKT2CASP3POLB | |
| SCHEMBL23726231 | 0.73 | KDM4E (0.38) | KDM4EALDH1A1AHRAKT2CASP3 | |
| SCHEMBL28903524 | 0.72 | KDM4E (0.41) | KDM4EALDH1A1AHRCASP3LMNA | |
| SCHEMBL18015434 | 0.71 | ADORA3 (0.55) | KDM4EALDH1A1METTL3AHRGRM5 | |
| SCHEMBL23726594 | 0.67 | MAPT (0.41) | KDM4EALDH1A1LMNAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115413275-A | Substituted 1,1 , -biphenyl compounds and methods of use thereof | 爱彼特生物制药公司 | 2022-11-29 | — | — | CN | disclosed |