Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 17/20 | 0.52 |
| ▸ | KDM6B | O15054 | 9/20 | 0.52 |
| ▸ | KDM4D | Q6B0I6 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | KDM4A | O75164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ASPH | Q12797 | 2/20 | 0.46 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.46 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.40 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29578794 | 0.92 | KDM4C (0.59) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL82604 | 0.92 | KDM4C (0.59) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| Hydrochloric Acid SCHEMBL1027857 | 0.90 | KDM4C (0.57) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL8686759 | 0.81 | ROCK2 (0.47) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| Nitrous Acid SCHEMBL27636084 | 0.79 | KDM4C (0.53) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| Nitrous Acid SCHEMBL29105410 | 0.78 | KDM4C (0.85) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| Nitrous Acid SCHEMBL28552198 | 0.78 | KDM4C (0.52) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL28904581 | 0.76 | KMT2A (0.46) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL229353 | 0.76 | KDM4C (0.53) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL30316868 | 0.76 | KDM4C (0.53) | KDM4CKDM6BKDM4DKDM4EKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111868037-A | Fused cyclic urea derivatives as CRHR2 antagonists | 拉夸里亚创药株式会社 | 2020-10-30 | — | — | CN | disclosed |