SCHEMBL229353

SCHEMBL229353

O=C(O)c1cnccc1F

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 10/20 0.53
KDM4E B2RXH2 4/20 0.53
KDM6B O15054 4/20 0.53
KDM4D Q6B0I6 3/20 0.53
TDP1 Q9NUW8 2/20 0.53
ALDH1A1 P00352 2/20 0.53
KDM4A O75164 2/20 0.53
MEN1 O00255 1/20 0.53
MAPT P10636 1/20 0.53
THRB P10828 1/20 0.53
KMT2A Q03164 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
NAPRT Q6XQN6 2/20 0.44
ASPH Q12797 2/20 0.42
KDM8 Q8N371 2/20 0.42
SIRT3 Q9NTG7 1/20 0.42
APP P05067 1/20 0.42
GAA P10253 1/20 0.42
HCAR3 P49019 1/20 0.42
HCAR2 Q8TDS4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30316868 1.00 KDM4C (0.53) KDM4CKDM4EKDM6BKDM4DTDP1
SCHEMBL29578794 0.83 KDM4C (0.59) KDM4CKDM4EKDM6BKDM4DTDP1
SCHEMBL82604 0.83 KDM4C (0.59) KDM4CKDM4EKDM6BKDM4DTDP1
SCHEMBL16414200 0.81 TDP1 (0.46) KDM4CKDM4EKDM6BKDM4DTDP1
SCHEMBL30849093 0.81 TDP1 (0.46) KDM4CKDM4EKDM6BKDM4DTDP1
Hydrochloric Acid SCHEMBL1027857 0.81 KDM4C (0.57) KDM4CKDM4EKDM6BKDM4DTDP1
SCHEMBL2579028 0.81 ALDH1A1 (0.52) KDM4CKDM4EKDM6BKDM4DTDP1
SCHEMBL1135627 0.81 SIRT3 (0.60) KDM4CKDM4EKDM6BKDM4DTDP1
SCHEMBL8688700 0.80 KEAP1 (0.43) KDM4CKDM4EKDM6BKDM4DTDP1
SCHEMBL29416303 0.79 KDM4C (0.65) KDM4CKDM4EKDM6BKDM4DTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116936810-B Positive pole piece of sodium ion battery and sodium ion battery 天鹏锂能技术(淮安)有限公司 2023-12-12 CN claimed
CN-116936810-A Positive pole piece of sodium ion battery and sodium ion battery 天鹏锂能技术(淮安)有限公司 2023-10-24 CN claimed
US-12559462-B2 Pyrimidine derivatives as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto ARENA PHARMACEUTICALS, INC. (US) 2026-02-24 US disclosed
US-12545684-B2 CDK2 inhibitors BLUEPRINT MEDICINES CORPORATION (US) 2026-02-10 US disclosed
US-20250270172-A1 Pyrimidine Derivatives As Modulators of the 5-HT2A Serotonin Receptor Useful For The Treatment of Disorders Related Thereto ARENA PHARMACEUTICALS, INC. (US) 2025-08-28 US disclosed
US-20250236608-A1 EGFR INHIBITORS BLUEPRINT MEDICINES CORPORATION 2025-07-24 US disclosed
EP-4236937-B1 PYRIMIDINE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO ARENA PHARM INC (US) 2025-07-23 EP disclosed
CN-120136779-A Preparation method of fluoro-azabenzene and derivatives thereof 南开大学 2025-06-13 CN disclosed
US-20250073249-A1 STEROID COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2025-03-06 US disclosed
CN-119325471-A EGFR inhibitors 缆图药品公司 2025-01-17 CN disclosed
US-20240383902-A1 CDK2 INHIBITORS BLUEPRINT MEDICINES CORPORATION 2024-11-21 US disclosed
CN-101605794-B Azabenzofuranyl compounds and methods of use GENENTECH INC US 2013-06-12 CN disclosed
CN-102947305-A Compounds and methods for kinase modulation and indications therefor PLEXXIKON INC 2013-02-27 CN disclosed
CN-102369188-A Substituted nicotinamides as KCNQ2/3 modulators GRUENENTHAL GMBH 2012-03-07 CN disclosed
US-20120004208-A1 BENZOYL-PIPERIDINE DERIVATIVES AS DUAL MODULATORS OF THE 5-HT2A AND D3 RECEPTORS GOBBI LUCA (CH) 2012-01-05 US disclosed
US-8039490-B2 Benzoyl-piperidine derivatives as dual modulators of the 5-HT2A and D3 receptors HOFFMANN-LA ROCHE INC. (US) 2011-10-18 US disclosed
US-20090023733-A1 Piperidine Derivatives, Their Process for Preparation, Their Use as Therapeutic Agents and Pharmaceutical Compositions Containing Them ASTRAZENECA AB (SE) 2009-01-22 US disclosed
CN-101223169-A Pyrrolo [2, 3-b ] pyridine derivative protein kinase inhibitors PLEXXIKON INC (US) 2008-07-16 CN disclosed
US-5641727-A Herbicidal 1-pyridyltetrazolinones NIHON BAYER AGROCHEM K.K. (JP) 1997-06-24 US disclosed
EP-0692482-A2 1-pyridyltetrazolinone derivatives NIHON BAYER AGROCHEM K.K. (JP) 1996-01-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250270172-A1 Pyrimidine Derivatives As Modulators of the 5-HT2A Serotonin Receptor Useful For The Treatment of Disorders Related Thereto HTR2A, HTR5A, HTR1A KDM4C 4140/4885KDM4E 3934/4885KDM6B 1486/4885
US-20120004208-A1 BENZOYL-PIPERIDINE DERIVATIVES AS DUAL MODULATORS OF THE 5-HT2A AND D3 RECEPTORS HTR2A, HTR3A, HTR2C KDM4C 1762/4885KDM4E 1738/4885KDM6B 1644/4885
US-20090023733-A1 Piperidine Derivatives, Their Process for Preparation, Their Use as Therapeutic Agents and Pharmaceutical Compositions Containing Them CCR3, CCR1, CCR5 KDM4C 2144/4885KDM4E 2869/4885KDM6B 3871/4885
US-12559462-B2 Pyrimidine derivatives as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto HTR2C, HTR1A, HTR2A KDM4C 3084/4885KDM4E 4301/4885KDM6B 3010/4885
US-20250236608-A1 EGFR INHIBITORS EGFR, ERBB2, ERBB3 KDM4C 4433/4885KDM4E 3399/4885KDM6B 3280/4885
US-20240383902-A1 CDK2 INHIBITORS CDK2, CDK20, CDK2AP1 KDM4C 2990/4885KDM4E 2160/4885KDM6B 2112/4885
US-20250073249-A1 STEROID COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF NR5A1, CYP17A1, AR KDM4C 4409/4885KDM4E 3740/4885KDM6B 4061/4885
US-12545684-B2 CDK2 inhibitors CDK2, CDK4, CDK1 KDM4C 1618/4885KDM4E 1727/4885KDM6B 3121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.