Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.62 |
| ▸ | CA1 | P00915 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | CA2 | P00918 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | CA9 | Q16790 | 2/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.62 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.62 |
| ▸ | CA4 | P22748 | 1/20 | 0.62 |
| ▸ | CA6 | P23280 | 1/20 | 0.62 |
| ▸ | CA7 | P43166 | 1/20 | 0.62 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL9800701 | 0.83 | KDM4E (0.75) | ALDH1A1KDM4ECA1HPGDCA2 | |
| Salicylic Acid SCHEMBL4295686 | 0.83 | KDM4E (0.82) | ALDH1A1KDM4ECA1HPGDCA2 | |
| Salicylic Acid SCHEMBL31490109 | 0.83 | KDM4E (0.82) | ALDH1A1KDM4ECA1HPGDCA2 | |
| Salicylic Acid SCHEMBL28820609 | 0.81 | KDM4E (0.78) | ALDH1A1KDM4ECA1HPGDCA2 | |
| Salicylic Acid SCHEMBL8176134 | 0.81 | KDM4E (0.78) | ALDH1A1KDM4ECA1HPGDCA2 | |
| Benzene SCHEMBL6746153 | 0.81 | CA2 (0.58) | ALDH1A1CA1CA2SMN1; SMN2CA9 | |
| SCHEMBL146561 | 0.81 | CA2 (0.58) | ALDH1A1CA1CA2SMN1; SMN2CA9 | |
| Salicylic Acid SCHEMBL30570927 | 0.81 | ALDH1A1 (0.95) | ALDH1A1KDM4ECA1HPGDCA2 | |
| Salicylic Acid SCHEMBL9228055 | 0.80 | KDM4E (0.75) | ALDH1A1KDM4ECA1HPGDCA2 | |
| Salicylic Acid SCHEMBL30940555 | 0.80 | KDM4E (0.75) | ALDH1A1KDM4ECA1HPGDCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112098497-B | Method for electrochemically identifying and detecting aspartic acid enantiomer and application | 常州工学院 | 2023-03-17 | — | — | CN | claimed |
| CN-112098497-A | Method for electrochemically identifying and detecting aspartic acid enantiomer and application | 常州工学院 | 2020-12-18 | — | — | CN | claimed |
| CN-112098497-B | Method for electrochemically identifying and detecting aspartic acid enantiomer and application | 常州工学院 | 2023-03-17 | — | — | CN | disclosed |
| CN-112098497-A | Method for electrochemically identifying and detecting aspartic acid enantiomer and application | 常州工学院 | 2020-12-18 | — | — | CN | disclosed |