Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.42 |
| ▸ | QDPR | P09417 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24802975 | 0.83 | SLC6A4 (0.41) | SLC6A4QDPR | |
| SCHEMBL31223021 | 0.81 | QDPR (0.44) | SLC6A4QDPR | |
| SCHEMBL16101100 | 0.79 | SLC6A4 (0.46) | SLC6A4QDPRKDM4ELMNAPOLB | |
| SCHEMBL17897342 | 0.79 | QDPR (0.54) | QDPR | |
| SCHEMBL18620920 | 0.76 | QDPR (0.47) | QDPR | |
| SCHEMBL28517116 | 0.75 | SLC6A4 (0.55) | SLC6A4HTR6 | |
| SCHEMBL23551386 | 0.75 | SLC6A4 (0.49) | SLC6A4QDPRKDM4ELMNAPOLB | |
| SCHEMBL429388 | 0.74 | GAA (0.39) | KDM4ELMNAPOLBHSD17B10 | |
| SCHEMBL459256 | 0.74 | ALDH1A1 (0.48) | KDM4ELMNAHSD17B10 | |
| SCHEMBL28513402 | 0.73 | HTR6 (0.38) | SLC6A4QDPRHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112243439-A | Pyrrolo [2,3-B ] pyridines or pyrrolo [2,3-B ] pyrazines as HPK1 inhibitors and uses thereof | 百济神州有限公司 | 2021-01-19 | — | — | CN | disclosed |