Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 11/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TNKS | O95271 | 2/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GPR3 | P46089 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27648564 | 0.81 | JAK2 (0.53) | ALDH1A1GPR3HSD17B10PABPC1 | |
| SCHEMBL28188584 | 0.79 | POLB (0.55) | ALDH1A1KDM4EMEN1LMNAKMT2A | |
| SCHEMBL23131942 | 0.79 | PARP1 (0.58) | PARP1ALDH1A1TNKSPARP15TNKS2 | |
| SCHEMBL28164562 | 0.75 | AHR (0.53) | KDM4ECYP1A2PABPC1TSHR | |
| SCHEMBL15453221 | 0.72 | PABPC1 (0.59) | ALDH1A1KDM4EMEN1CYP1A2KMT2A | |
| SCHEMBL29506423 | 0.72 | PABPC1 (0.59) | ALDH1A1KDM4EMEN1CYP1A2KMT2A | |
| SCHEMBL27797313 | 0.72 | PARP1 (0.55) | PARP1ALDH1A1TNKSPARP15TNKS2 | |
| SCHEMBL28166021 | 0.71 | JAK2 (0.38) | ALDH1A1PABPC1 | |
| SCHEMBL2231861 | 0.70 | ALDH1A1 (0.53) | ALDH1A1KDM4EMEN1LMNAKMT2A | |
| SCHEMBL28334523 | 0.70 | PABPC1 (0.36) | HSD17B10PABPC1TSHRCASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112279810-A | 6-oxo-5, 6-dihydrophenanthridine-4-formamide compound, preparation method, pharmaceutical composition and application | 北京华氏开元医药科技有限公司 | 2021-01-29 | — | — | CN | claimed |
| CN-112279810-B | 6-oxo-5, 6-dihydrophenanthridine-4-formamide compound, preparation method, pharmaceutical composition and application | 北京华氏开元医药科技有限公司 | 2021-05-18 | — | — | CN | disclosed |
| CN-112279810-B | 6-oxo-5, 6-dihydrophenanthridine-4-formamide compound, preparation method, pharmaceutical composition and application | 北京华氏开元医药科技有限公司 | 2021-05-18 | — | — | CN | disclosed |
| CN-112279810-B | 6-oxo-5, 6-dihydrophenanthridine-4-formamide compound, preparation method, pharmaceutical composition and application | 北京华氏开元医药科技有限公司 | 2021-05-18 | — | — | CN | disclosed |
| CN-112279810-A | 6-oxo-5, 6-dihydrophenanthridine-4-formamide compound, preparation method, pharmaceutical composition and application | 北京华氏开元医药科技有限公司 | 2021-01-29 | — | — | CN | disclosed |
| CN-112279810-A | 6-oxo-5, 6-dihydrophenanthridine-4-formamide compound, preparation method, pharmaceutical composition and application | 北京华氏开元医药科技有限公司 | 2021-01-29 | — | — | CN | disclosed |
| CN-112279810-A | 6-oxo-5, 6-dihydrophenanthridine-4-formamide compound, preparation method, pharmaceutical composition and application | 北京华氏开元医药科技有限公司 | 2021-01-29 | — | — | CN | disclosed |