Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 12/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 10/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 9/20 | 0.41 |
| ▸ | TSHR | P16473 | 7/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28513248 | 0.79 | VDR (0.38) | LMNACYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL3317844 | 0.77 | CA1 (0.36) | LMNATSHRHTTAGTR2 | |
| SCHEMBL15927904 | 0.74 | ADAM17 (0.44) | LMNACYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL15337105 | 0.74 | ADAM17 (0.44) | LMNACYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL15927894 | 0.74 | ADAM17 (0.44) | LMNACYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL3992603 | 0.74 | AGTR2 (0.41) | LMNACYP2C9CYP2C19TSHRCYP1A2 | |
| SCHEMBL18506652 | 0.73 | ADAM17 (0.45) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL18506747 | 0.73 | ADAM17 (0.45) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL30707059 | 0.73 | ADAM17 (0.45) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL20565598 | 0.71 | L3MBTL1 (0.48) | LMNAL3MBTL1CYP3A4TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112239398-A | Dimethylcyclobutanone compound, dimethylcyclobutane compound and preparation method thereof | 信越化学工业株式会社 | 2021-01-19 | — | — | CN | disclosed |