SCHEMBL28906169

SCHEMBL28906169

C=C(C)C(=O)OCCOP(=O)(OCCCC)OCC[N+](C)(C)C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.49
CYP3A4 P08684 2/20 0.46
LMNA P02545 1/20 0.44
ESR1 P03372 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
CDC25A P30304 1/20 0.44
AGTR1 P30556 1/20 0.44
AKT1 P31749 1/20 0.44
ADRA1A P35348 1/20 0.44
KCNH2 Q12809 1/20 0.44
THRB P10828 1/20 0.43
ACHE P22303 3/20 0.40
CHRM5 P08912 1/20 0.39
CHRM1 P11229 1/20 0.39
CHRM3 P20309 1/20 0.39
ADRA1D P25100 1/20 0.38
PTAFR P25105 1/20 0.38
HTR1D P28221 1/20 0.38
HTR2C P28335 1/20 0.38
ADRA1B P35368 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8757327 0.90 TSHR (0.59) TSHRCYP3A4THRB
SCHEMBL28329138 0.88 TSHR (0.51) TSHRLMNAESR1ADORA3CDC25A
SCHEMBL368310 0.87 LMNA (0.56) TSHRLMNAESR1ADORA3CDC25A
Phosphocholine SCHEMBL28111186 0.85 TSHR (0.54) TSHRLMNAESR1ADORA3CDC25A
SCHEMBL18022725 0.85 THRB (0.42) TSHRLMNAADRA1ATHRBCHRM5
SCHEMBL481622 0.84 TSHR (0.70) TSHRCYP3A4THRB
SCHEMBL28906170 0.83 THRB (0.47) TSHRCYP3A4LMNAESR1ADORA3
Phosphoric Acid SCHEMBL2037296 0.83 THRB (0.43) TSHRCYP3A4LMNAESR1ADORA3
SCHEMBL28595957 0.83 TSHR (0.60) TSHRLMNAESR1ADORA3CDC25A
Phosphocholine SCHEMBL1949342 0.83 TSHR (0.51) TSHRLMNAESR1ADORA3CDC25A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115301214-A Choline phosphoric acid composite magnetic nano material and preparation method and application thereof 暨南大学 2022-11-08 CN disclosed
CN-115301214-A Choline phosphoric acid composite magnetic nano material and preparation method and application thereof 暨南大学 2022-11-08 CN disclosed