Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.61 |
| ▸ | HTR2C | P28335 | 2/20 | 0.61 |
| ▸ | DRD2 | P14416 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TSPO | P30536 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL823080 | 0.86 | HTR2A (0.66) | HTR2AHTR2CDRD2KDM4EMAPT | |
| SCHEMBL6990745 | 0.86 | DRD2 (0.52) | HTR2AHTR2CDRD2KDM4EMAPT | |
| SCHEMBL29069328 | 0.85 | DRD2 (0.51) | HTR2AHTR2CDRD2KDM4EMAPT | |
| SCHEMBL28906516 | 0.85 | HTR2A (0.62) | HTR2AHTR2CDRD2CNR1TUBB4A | |
| SCHEMBL24098774 | 0.82 | PPARG (0.61) | HTR2AHTR2CDRD2KDM4EMAPT | |
| SCHEMBL30218292 | 0.82 | PPARG (0.61) | HTR2AHTR2CDRD2KDM4EMAPT | |
| SCHEMBL28906369 | 0.82 | MAPT (0.55) | HTR2AHTR2CDRD2MAPTHPGD | |
| SCHEMBL28906371 | 0.82 | HTR2A (0.61) | HTR2AHTR2CDRD2KDM4EMAPT | |
| SCHEMBL28906377 | 0.82 | PTGS2 (0.49) | HTR2AHTR2CDRD2MAPTPTGS2 | |
| SCHEMBL28906367 | 0.81 | HTR2A (0.64) | HTR2AHTR2CDRD2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304533-B | Bisindolemethane type alpha-glucosidase inhibitor and preparation method and application thereof | 中国医学科学院药用植物研究所云南分所 | 2024-04-12 | — | — | CN | disclosed |
| CN-117567447-A | Thiophene-containing bis-indolomethane type a-glucosidase inhibitor and preparation method and application thereof | 中国医学科学院药用植物研究所云南分所 | 2024-02-20 | — | — | CN | disclosed |
| CN-115304533-A | Bis-indole methane type alpha-glucosidase inhibitor and preparation method and application thereof | 中国医学科学院药用植物研究所云南分所 | 2022-11-08 | — | — | CN | disclosed |