Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.63 |
| ▸ | CTSB | P07858 | 3/20 | 0.63 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.63 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.63 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.63 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.63 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | F3 | P13726 | 2/20 | 0.62 |
| ▸ | P4HB | P07237 | 1/20 | 0.62 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | XDH | P47989 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | DPP4 | P27487 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10384464 | 0.86 | GABRA3 (0.84) | CTSLCTSBCAPN1GABRA3GABRA2 | |
| SCHEMBL1603827 | 0.86 | CHRNA7 (0.75) | CTSLCTSBCAPN1GABRA3GABRA2 | |
| SCHEMBL1603828 | 0.86 | CHRNA7 (0.75) | CTSLCTSBCAPN1GABRA3GABRA2 | |
| SCHEMBL26113846 | 0.85 | CTSB (0.86) | CTSLCTSBCAPN1GABRA3GABRA2 | |
| SCHEMBL28906362 | 0.83 | CAPN1 (0.66) | CTSLCTSBCAPN1TDP1P4HB | |
| SCHEMBL28906376 | 0.83 | CHRNA7 (0.73) | TDP1MAPTRAB9AMEN1ALDH1A1 | |
| SCHEMBL28906356 | 0.83 | CTSL (0.62) | CTSLCTSBCAPN1TNFRSF1ATDP1 | |
| SCHEMBL28339980 | 0.83 | GABRA3 (0.78) | CTSLCTSBGABRA3GABRA2GABRB2 | |
| SCHEMBL4139154 | 0.83 | GABRA3 (0.78) | CTSLCTSBGABRA3GABRA2GABRB2 | |
| SCHEMBL7180313 | 0.80 | TNFRSF1A (0.86) | CTSLCTSBCAPN1TNFRSF1ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304513-A | Chalcone derivative with anti-inflammatory activity and synthesis method and application thereof | 湖北科技学院 | 2022-11-08 | — | — | CN | disclosed |