Phenanthroline

Phenanthroline

SCHEMBL28906609

CC(=O)n1ccnc1.[Ru].c1cnc2c(c1)ccc1cccnc12

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.47
LMNA P02545 3/20 0.47
CCR1 P32246 3/20 0.47
CCR5 P51681 3/20 0.47
CCR8 P51685 3/20 0.47
KDM4E B2RXH2 2/20 0.47
MAPT P10636 2/20 0.47
HTT P42858 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
MMP2 P08253 2/20 0.47
TSHR P16473 2/20 0.47
GMNN O75496 1/20 0.47
TP53 P04637 1/20 0.47
HSP90AA1 P07900 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2D6 P10635 1/20 0.47
MMP9 P14780 1/20 0.47
ALOX15 P16050 1/20 0.47
NFKB1 P19838 1/20 0.47
MMP8 P22894 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinoline SCHEMBL27817062 0.82 ALDH1A1 (0.50) KDM4EMAPTHTTALOX15ALDH1A1
Anthracene SCHEMBL7109280 0.80 CYP19A1 (0.44) LMNACYP3A4ALDH1A1
Phenanthroline SCHEMBL28097109 0.77 LMNA (0.73) TDP1LMNACCR1CCR5CCR8
SCHEMBL26238 0.77
SCHEMBL25507680 0.77
Phenanthroline SCHEMBL22401704 0.75 LMNA (0.70) TDP1LMNACCR1CCR5CCR8
Phenanthroline SCHEMBL4881417 0.75 LMNA (0.70) TDP1LMNACCR1CCR5CCR8
Phenanthroline SCHEMBL5998459 0.74 TDP1 (0.61) TDP1LMNACCR1CCR5CCR8
Phenanthroline SCHEMBL29521774 0.73 LMNA (0.67) TDP1LMNACCR1CCR5CCR8
Phenanthroline SCHEMBL29278213 0.73 LMNA (0.67) TDP1LMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112321731-B Photoactivated tea sapogenin cellulose nano material and preparation method and application thereof 华南理工大学 2021-09-21 CN disclosed
CN-112321731-A Photoactivated tea sapogenin cellulose nano material and preparation method and application thereof 华南理工大学 2021-02-05 CN disclosed