Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phenanthroline. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.67 |
| ▸ | CCR1 | P32246 | 3/20 | 0.67 |
| ▸ | CCR5 | P51681 | 3/20 | 0.67 |
| ▸ | CCR8 | P51685 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | MMP2 | P08253 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | GMNN | O75496 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | MMP9 | P14780 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.67 |
| ▸ | MMP8 | P22894 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenanthroline SCHEMBL3408768 | 1.00 | LMNA (0.67) | LMNACCR1CCR5CCR8KDM4E | |
| Phenanthroline SCHEMBL22401704 | 0.98 | LMNA (0.70) | LMNACCR1CCR5CCR8KDM4E | |
| Phenanthroline SCHEMBL4881417 | 0.98 | LMNA (0.70) | LMNACCR1CCR5CCR8KDM4E | |
| Phenanthroline SCHEMBL29278213 | 0.96 | LMNA (0.67) | LMNACCR1CCR5CCR8KDM4E | |
| Phenanthroline SCHEMBL28097109 | 0.91 | LMNA (0.73) | LMNACCR1CCR5CCR8KDM4E | |
| Phenanthroline SCHEMBL27878295 | 0.87 | KDM4E (0.80) | LMNACCR1CCR5CCR8KDM4E | |
| Phenanthroline SCHEMBL28776402 | 0.86 | LMNA (0.59) | LMNACCR1CCR5CCR8KDM4E | |
| Phenanthroline SCHEMBL2532986 | 0.86 | KDM4E (0.64) | LMNACCR1CCR5CCR8KDM4E | |
| Phenanthroline SCHEMBL29278214 | 0.86 | KDM4E (0.64) | LMNACCR1CCR5CCR8KDM4E | |
| Phenanthroline SCHEMBL29188565 | 0.86 | KDM4E (0.64) | LMNACCR1CCR5CCR8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250207163-A1 | METHODS AND APPARATUS FOR SYNTHESIZING NUCLEIC ACIDS | TRILINK BIOTECHNOLOGIES, LLC | 2025-06-26 | — | — | US | disclosed |
| CN-115959987-B | Catalyst composition for preparing unsaturated carboxylate by carbon dioxide and ethylene | 华东理工大学 | 2025-05-09 | — | — | CN | disclosed |
| CN-119916644-A | Photosensitive resin composition containing alkynyl anthracene photosensitizer and application thereof | 湖南初源新材料股份有限公司 | 2025-05-02 | — | — | CN | disclosed |
| EP-4499824-A1 | METHODS AND APPARATUS FOR SYNTHESIZING NUCLEIC ACIDS | Molecular Assemblies, Inc. (US) | 2025-02-05 | — | — | EP | disclosed |
| EP-4121407-B1 | CATALYTIC PROCESS FOR PREPARING AN ALPHA, BETA-ETHYLENICALLY UNSATURATED CARBOXYLIC ACID SALT | BASF SE (DE) | 2024-03-06 | — | — | EP | disclosed |
| WO-2023183569-A1 | METHODS AND APPARATUS FOR SYNTHESIZING NUCLEIC ACIDS | Molecular Assemblies, Inc. (US) | 2023-09-28 | — | — | WO | disclosed |
| US-20230138524-A1 | CATALYTIC PROCESS FOR PREPARING AN a,ß-ETHYLENICALLY UNSATURATED CARBOXYLIC ACID SALT | BASF SE (DE) | 2023-05-04 | — | — | US | disclosed |
| CN-115959987-A | Catalyst composition for preparing unsaturated carboxylate from carbon dioxide and ethylene | 华东理工大学 | 2023-04-14 | — | — | CN | disclosed |
| EP-4121407-A1 | Catalytic process for preparing an alpha, Beta-ethylenically unsaturated carboxylic acid salt | BASF SE (DE) | 2023-01-25 | — | — | EP | disclosed |
| CN-108884010-B | Process for preparing unsaturated carboxylic acid salts | 巴斯夫欧洲公司 | 2022-11-08 | — | — | CN | disclosed |
| CN-115298157-A | Catalytic process for preparing alpha, beta-ethylenically unsaturated carboxylic acid salts | 巴斯夫欧洲公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-106458823-B | Process for preparing unsaturated carboxylic acid salts | 巴斯夫欧洲公司 | 2022-04-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230138524-A1 | CATALYTIC PROCESS FOR PREPARING AN a,ß-ETHYLENICALLY UNSATURATED CARBOXYLIC ACID SALT | ADH1C, ADH1A, COASY | LMNA 1590/4885CCR1 1086/4885CCR5 1819/4885 |
| US-20250207163-A1 | METHODS AND APPARATUS FOR SYNTHESIZING NUCLEIC ACIDS | RNGTT, POLRMT, POLN | LMNA 698/4885CCR1 4545/4885CCR5 4386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.