Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 9/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6376947 | 0.83 | ALDH1A1 (0.52) | ALDH1A1TDP1HSD17B10LMNACYP1A2 | |
| SCHEMBL9015211 | 0.80 | ALDH1A1 (0.44) | ALDH1A1TDP1GPR35HSD17B10TSHR | |
| SCHEMBL7782705 | 0.80 | MAPK1 (0.44) | ALDH1A1TDP1TSHRMAPTLMNA | |
| SCHEMBL12778730 | 0.78 | — | — | |
| SCHEMBL1774516 | 0.78 | — | — | |
| SCHEMBL31472833 | 0.78 | — | — | |
| SCHEMBL28595029 | 0.78 | ALDH1A1 (0.44) | ALDH1A1TDP1GPR35TSHRMAPT | |
| SCHEMBL8128194 | 0.77 | MAPT (0.45) | ALDH1A1TDP1CYP3A4MAPTLMNA | |
| SCHEMBL9229308 | 0.75 | HSD17B10 (0.46) | ALDH1A1TDP1HSD17B10TSHRMAPT | |
| SCHEMBL8044178 | 0.75 | ALDH1A1 (0.35) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8211252-B2 | Furazane derivatives, preparation thereof and energetic compositions containing them | EURENCO (FR) | 2012-07-03 | — | — | US | claimed |
| US-20100132856-A1 | FURAZANE DERIVATIVES, PREPARATION THEREOF AND ENERGETIC COMPOSITIONS CONTAINING THEM | SNPE MATERIAUX ENERGETIQUES (FR) | 2010-06-03 | — | — | US | claimed |
| US-8211252-B2 | Furazane derivatives, preparation thereof and energetic compositions containing them | EURENCO (FR) | 2012-07-03 | — | — | US | disclosed |
| US-20100132856-A1 | FURAZANE DERIVATIVES, PREPARATION THEREOF AND ENERGETIC COMPOSITIONS CONTAINING THEM | SNPE MATERIAUX ENERGETIQUES (FR) | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100132856-A1 | FURAZANE DERIVATIVES, PREPARATION THEREOF AND ENERGETIC COMPOSITIONS CONTAINING THEM | NOX5, COX5A, TXN2 | ALDH1A1 315/4885TDP1 1555/4885GPR35 333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.