Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | DBH | P09172 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2890666 | 0.75 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL1774516 | 0.66 | — | — | |
| SCHEMBL6376947 | 0.66 | ALDH1A1 (0.52) | ALDH1A1 | |
| SCHEMBL28667238 | 0.66 | TSHR (0.41) | ALDH1A1DBH | |
| SCHEMBL8042596 | 0.66 | CYP2A6 (0.45) | ALDH1A1 | |
| SCHEMBL8043920 | 0.66 | CYP19A1 (0.52) | ALDH1A1 | |
| SCHEMBL8033685 | 0.65 | LMNA (0.48) | ALDH1A1 | |
| SCHEMBL9015211 | 0.64 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL7782705 | 0.63 | MAPK1 (0.44) | ALDH1A1 | |
| SCHEMBL31472833 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |