Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19834693 | 0.84 | PTGS1 (0.43) | HPGDPTGS1PTGS2AKR1C3MAPT | |
| SCHEMBL19834690 | 0.81 | NPSR1 (0.47) | HPGDPTGS2AKR1C3MAPTMAPK1 | |
| SCHEMBL19834696 | 0.80 | AKR1C3 (0.48) | HPGDPTGS1PTGS2AKR1C3MAPT | |
| SCHEMBL10580853 | 0.78 | AKR1C3 (0.50) | HPGDPTGS1PTGS2AKR1C3MAPT | |
| SCHEMBL31086202 | 0.78 | AKR1C3 (0.50) | HPGDPTGS1PTGS2AKR1C3MAPT | |
| SCHEMBL28527900 | 0.76 | BCL2 (0.51) | HPGDAKR1C3MAPTMAPK1ALDH1A1 | |
| SCHEMBL28570168 | 0.76 | ALDH1A1 (0.44) | HPGDPTGS1PTGS2AKR1C3MAPT | |
| SCHEMBL28121439 | 0.75 | MAPT (0.58) | HPGDPTGS1PTGS2AKR1C3MAPT | |
| SCHEMBL10007412 | 0.74 | ALDH1A1 (0.59) | HPGDAKR1C3MAPTMAPK1ALDH1A1 | |
| SCHEMBL19834641 | 0.74 | AKR1C3 (0.53) | HPGDAKR1C3MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107428646-B | Compounds, resins, and methods for their purification, and uses thereof | 三菱瓦斯化学株式会社 | 2021-03-02 | — | — | CN | disclosed |