Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGER | Q15109 | 2/20 | 0.62 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MPL | P40238 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | VCP | P55072 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 3/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.50 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.50 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19851004 | 0.90 | AGER (0.70) | AGERALOX5NPY5RNPC1RAB9A | |
| SCHEMBL31126441 | 0.85 | VCP (0.72) | ALOX5NPY5RNPC1RAB9AMPL | |
| SCHEMBL206171 | 0.84 | ALOX5 (0.60) | AGERALOX5NPC1RAB9AMEN1 | |
| SCHEMBL29276772 | 0.84 | AGER (0.75) | AGERALOX5NPY5RNPC1RAB9A | |
| SCHEMBL208205 | 0.82 | AGER (0.59) | AGERALOX5NPC1RAB9AMEN1 | |
| SCHEMBL31126428 | 0.82 | ALOX5 (0.78) | ALOX5NPY5RNPC1RAB9AMEN1 | |
| SCHEMBL205404 | 0.81 | VCP (0.65) | AGERALOX5NPC1RAB9AMEN1 | |
| SCHEMBL205146 | 0.80 | AGER (0.65) | AGERALOX5NPC1RAB9AMEN1 | |
| SCHEMBL5026675 | 0.80 | ALOX5 (0.64) | ALOX5NPY5RNPC1RAB9AMEN1 | |
| SCHEMBL31126438 | 0.80 | ALOX5 (0.64) | ALOX5NPY5RNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107629022-B | Antibacterial synergist and preparation method and application thereof | 上海医药工业研究院 | 2024-11-12 | — | — | CN | disclosed |
| CN-115124487-A | Preparation method and application of arylimino thiazole compounds | 华东理工大学 | 2022-09-30 | — | — | CN | disclosed |