Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | KDM6B | O15054 | 1/20 | 0.44 |
| ▸ | KDM5C | P41229 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.44 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22049082 | 0.80 | L3MBTL1 (0.55) | KDM4EL3MBTL1ALOX15HTTPSMD14 | |
| SCHEMBL23112595 | 0.76 | PSMD14 (0.48) | MAPK1KDM4EL3MBTL1ALOX15HTT | |
| SCHEMBL2199238 | 0.76 | PSMD14 (0.48) | MAPK1KDM4EL3MBTL1ALOX15HTT | |
| SCHEMBL31606412 | 0.75 | PSMD14 (0.47) | MAPK1KDM4EL3MBTL1ALOX15HTT | |
| SCHEMBL31413421 | 0.75 | MAPK1 (0.44) | MAPK1KDM4EL3MBTL1ALOX15HTT | |
| SCHEMBL27141675 | 0.75 | MAPK1 (0.44) | MAPK1KDM4EL3MBTL1ALOX15HTT | |
| SCHEMBL23112645 | 0.75 | PSMD14 (0.47) | MAPK1KDM4EL3MBTL1ALOX15HTT | |
| SCHEMBL2201313 | 0.75 | ALPL (0.47) | MAPK1KDM4EL3MBTL1ALOX15HTT | |
| SCHEMBL12076107 | 0.74 | ALOX15 (0.54) | MAPK1KDM4EKDM6BKDM5CKDM4C | |
| SCHEMBL23535787 | 0.74 | LCK (0.55) | MAPK1KDM4EKDM6BKDM5CKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448919-A | Marine-derived naphthyridine anti-inflammatory active compound and preparation method thereof | 滨州医学院附属医院 | 2022-12-09 | — | — | CN | disclosed |