Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 7/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20582046 | 0.84 | MIF (0.48) | CTSSCTSKRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL28909512 | 0.84 | MIF (0.48) | CTSSCTSKRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL28909466 | 0.84 | ALDH1A1 (0.52) | CTSKRAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL28909455 | 0.78 | RAB9A (0.47) | CTSSCTSKRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL28909447 | 0.78 | RAB9A (0.47) | CTSSCTSKRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL31456961 | 0.76 | CTSS (0.56) | CTSSCTSKRAB9ATSHRLMNA | |
| SCHEMBL6285264 | 0.76 | CTSS (0.56) | CTSSCTSKRAB9ATSHRLMNA | |
| SCHEMBL5729170 | 0.74 | CTSS (0.54) | CTSSCTSKTSHRLMNAPPARG | |
| SCHEMBL10774088 | 0.74 | CTSS (0.51) | CTSSCTSKRAB9ASMN1; SMN2TSHR | |
| SCHEMBL30561258 | 0.73 | CTSS (0.50) | CTSSCTSKRAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115322151-A | Method for synthesizing chiral multi-stereocenter pyrazolidine compounds by copper catalysis | 河南师范大学 | 2022-11-11 | — | — | CN | disclosed |