Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TACR2 | P21452 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19640069 | 0.77 | ALOX5 (0.51) | ALDH1A1LMNAFDPSKMT2APDE4B | |
| SCHEMBL19640094 | 0.75 | ALDH1A1 (0.47) | ALDH1A1LMNAFDPSKMT2APDE4B | |
| SCHEMBL19655519 | 0.74 | ALDH1A1 (0.44) | ALDH1A1LMNAFDPSKMT2APDE4B | |
| SCHEMBL1231147 | 0.74 | FDPS (0.69) | ALDH1A1LMNACA12CA2CA9 | |
| SCHEMBL29924333 | 0.74 | FDPS (0.69) | ALDH1A1LMNACA12CA2CA9 | |
| SCHEMBL433948 | 0.74 | ALDH1A1 (0.64) | ALDH1A1LMNACA12CA2CA9 | |
| SCHEMBL8194204 | 0.74 | PDE4B (0.44) | ALDH1A1LMNACA12CA2CA9 | |
| SCHEMBL20982802 | 0.73 | FDPS (0.42) | ALDH1A1LMNACA12CA2CA9 | |
| SCHEMBL1889208 | 0.73 | FDPS (0.51) | ALDH1A1LMNAFDPSKMT2APDE4B | |
| SCHEMBL12723248 | 0.72 | PDE4B (0.45) | ALDH1A1LMNACA12CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-B | Apoptosis inhibitors | 北京生命科学研究所 | 2022-10-04 | — | — | CN | disclosed |