Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 7/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 7/20 | 0.46 |
| ▸ | GABRP | O00591 | 6/20 | 0.46 |
| ▸ | GABRD | O14764 | 6/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 6/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 6/20 | 0.46 |
| ▸ | GABRE | P78334 | 6/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 6/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 6/20 | 0.46 |
| ▸ | GABRG3 | Q99928 | 6/20 | 0.46 |
| ▸ | GABRQ | Q9UN88 | 6/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL712413 | 0.87 | CYP1A2 (0.50) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL18674160 | 0.85 | TSHR (0.42) | SMN1; SMN2NPC1LMNAMAPK1RAB9A | |
| SCHEMBL2108310 | 0.83 | MAPK1 (0.56) | MAPTNPC1KDM4ELMNAMAPK1 | |
| SCHEMBL30640076 | 0.83 | MAPK1 (0.56) | MAPTNPC1KDM4ELMNAMAPK1 | |
| SCHEMBL9901416 | 0.83 | CYP1A2 (0.51) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL15669996 | 0.80 | KMT2A (0.44) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL2140228 | 0.78 | NPC1 (0.50) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL287558 | 0.78 | P4HTM (0.53) | MAPTALDH1A1KDM4EMAPK1 | |
| SCHEMBL749735 | 0.77 | CYP1A2 (0.45) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL347328 | 0.76 | CYP1A2 (0.51) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3388425-B1 | AMINOAZOLE DERIVATIVE | TEIJIN PHARMA LTD (JP) | 2020-08-05 | — | — | EP | disclosed |
| US-10689354-B2 | Aminoazole derivative | TEIJIN PHARMA LIMITED (JP) | 2020-06-23 | — | — | US | disclosed |
| US-20190031628-A1 | AMINOAZOLE DERIVATIVE | TEIJIN PHARMA LIMITED (JP) | 2019-01-31 | — | — | US | disclosed |
| EP-3388425-A1 | AMINOAZOLE DERIVATIVE | Teijin Pharma Limited (JP) | 2018-10-17 | — | — | EP | disclosed |
| CN-108368068-A | Amino Zole derivatives | 帝人制药株式会社 | 2018-08-03 | — | — | CN | disclosed |
| US-7732456-B2 | Pyridone derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-06-08 | — | — | US | disclosed |
| US-20070208046-A1 | Pyridone derivative | MSD K.K. (JP) | 2007-09-06 | — | — | US | disclosed |
| CN-1930126-A | Pyridone Derivatives | BANYU PHARMA CO LTD (JP) | 2007-03-14 | — | — | CN | disclosed |
| EP-1741703-A1 | PYRIDONE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-01-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208046-A1 | Pyridone derivative | CHRM1, XDH, MTR | GABRA1 2505/4885GABRG2 3591/4885GABRB3 2603/4885 |
| US-10689354-B2 | Aminoazole derivative | AR, NR3C2, NR5A1 | GABRA1 341/4885GABRG2 911/4885GABRB3 277/4885 |
| US-20190031628-A1 | AMINOAZOLE DERIVATIVE | AR, NR3C2, NR5A1 | GABRA1 341/4885GABRG2 911/4885GABRB3 277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.