Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | AGER | Q15109 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SPR | P35270 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30066845 | 0.78 | KDM4E (0.41) | PARP1KDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL29660941 | 0.76 | SPR (0.37) | PARP1KDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL29661036 | 0.75 | KDM4E (0.39) | PARP1KDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL29660938 | 0.74 | PDK2 (0.41) | PARP1KDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL7226244 | 0.73 | PARP1 (0.50) | PARP1 | |
| SCHEMBL22031860 | 0.72 | PARP1 (0.44) | PARP1KDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL29660939 | 0.70 | KDM4E (0.37) | PARP1KDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL4560363 | 0.68 | MKNK1 (0.50) | PARP1KDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL17503606 | 0.67 | KDM4E (0.43) | KDM4EALDH1A1MAPTL3MBTL1GAA | |
| SCHEMBL9516966 | 0.67 | HDAC4 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112739345-A | PIM kinase inhibitor compositions, methods and uses thereof | 斯奈普生物公司 | 2021-04-30 | — | — | CN | disclosed |