SCHEMBL29217062

SCHEMBL29217062

C[Si](C)(O)c1ccccc1.[KH]

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.48
ESR2 Q92731 1/20 0.48
NR1I2 O75469 9/20 0.47
NR1H2 P55055 2/20 0.42
NR1H3 Q13133 2/20 0.42
RORA P35398 1/20 0.40
RORC P51449 1/20 0.40
RORB Q92753 1/20 0.40
NR1H4 Q96RI1 1/20 0.40
MAPT P10636 1/20 0.38
CA4 P22748 2/20 0.35
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
GLA P06280 1/20 0.33
CA3 P07451 1/20 0.33
CA9 Q16790 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28912 0.97 ESR1 (0.50) ESR1ESR2NR1I2NR1H2NR1H3
SCHEMBL28018450 0.94 ESR1 (0.48) ESR1ESR2NR1I2NR1H2NR1H3
SCHEMBL31081430 0.94 NR1I2 (0.52) ESR1ESR2NR1I2NR1H2NR1H3
SCHEMBL2143983 0.94 ESR1 (0.48) ESR1ESR2NR1I2NR1H2NR1H3
Potassium SCHEMBL31414604 0.94 ESR1 (0.48) ESR1ESR2NR1I2NR1H2NR1H3
Magnesium Chloride Anhydrous SCHEMBL28382622 0.87 NR1I2 (0.43) ESR1ESR2NR1I2NR1H2NR1H3
SCHEMBL235602 0.81 NR1I2 (0.43) ESR1ESR2NR1I2NR1H2NR1H3
SCHEMBL273322 0.79 NR1H2 (0.59) ESR1ESR2NR1I2NR1H2NR1H3
SCHEMBL271787 0.79 ESR1 (0.50) ESR1ESR2NR1I2NR1H2NR1H3
SCHEMBL439492 0.78 ESR1 (0.48) ESR1ESR2NR1I2NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118085712-A Corrosion-resistant galvanized sheet, preparation process thereof and ship propeller using corrosion-resistant galvanized sheet 青岛永祥和环保科技有限公司 2024-05-28 CN disclosed