Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.37 |
| ▸ | REN | P00797 | 3/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22747833 | 0.75 | FOLH1 (0.41) | FOLH1MAPK8MAPK9MAPK10 | |
| SCHEMBL22760486 | 0.74 | FOLH1 (0.43) | FOLH1MAPK8MAPK9MAPK10EDNRA | |
| SCHEMBL22748245 | 0.73 | FOLH1 (0.42) | FOLH1MAPK8MAPK9MAPK10 | |
| SCHEMBL22748283 | 0.73 | FOLH1 (0.42) | FOLH1MAPK8MAPK9MAPK10 | |
| SCHEMBL22747841 | 0.71 | MAPK8 (0.52) | FOLH1MAPK8MAPK9 | |
| SCHEMBL22760554 | 0.71 | FOLH1 (0.40) | FOLH1MAPK8MAPK9MAPK10 | |
| SCHEMBL22747897 | 0.71 | FOLH1 (0.40) | FOLH1MAPK8MAPK9MAPK10EDNRA | |
| SCHEMBL22760555 | 0.70 | FOLH1 (0.39) | FOLH1MAPK8MAPK9MAPK10EDNRA | |
| SCHEMBL22747872 | 0.69 | KCNH2 (0.40) | — | |
| SCHEMBL22760357 | 0.67 | REN (0.38) | FOLH1RENMAPK8EDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112028815-A | Indole derivatives and medical application thereof | 中国药科大学 | 2020-12-04 | — | — | CN | disclosed |