Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28556217 | 0.88 | ALDH1A1 (0.43) | — | |
| SCHEMBL22747834 | 0.79 | KCNH2 (0.39) | KCNH2TAAR1DRD2HTR2A | |
| SCHEMBL22747875 | 0.79 | EDNRA (0.36) | — | |
| SCHEMBL22747877 | 0.76 | KCNH2 (0.38) | KCNH2TAAR1DRD2HTR2A | |
| SCHEMBL22747873 | 0.72 | MAT2A (0.43) | — | |
| SCHEMBL28912331 | 0.69 | FOLH1 (0.37) | — | |
| SCHEMBL22760046 | 0.69 | REN (0.38) | — | |
| SCHEMBL22760356 | 0.68 | MAT2A (0.43) | — | |
| SCHEMBL22747849 | 0.67 | FOLH1 (0.39) | — | |
| SCHEMBL22760096 | 0.67 | REN (0.39) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020244462-A1 | INDOLE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | 中国药科大学 | 2020-12-10 | — | — | WO | disclosed |
| CN-112028815-A | Indole derivatives and medical application thereof | 中国药科大学 | 2020-12-04 | — | — | CN | disclosed |