SCHEMBL28912366

SCHEMBL28912366

Cc1[c]c(C(=O)O)cc(C)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TPMT P51580 1/20 0.44
HCAR1 Q9BXC0 1/20 0.39
KDM4E B2RXH2 3/20 0.36
KMT2A Q03164 2/20 0.36
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
ALDH1A1 P00352 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
DAO P14920 3/20 0.34
HCAR2 Q8TDS4 2/20 0.33
SELL P14151 1/20 0.33
SELP P16109 1/20 0.33
SELE P16581 1/20 0.33
CSNK2A1 P68400 1/20 0.33
PIN1 Q13526 1/20 0.32
CNR2 P34972 1/20 0.32
SRD5A2 P31213 1/20 0.31
NOTUM Q6P988 1/20 0.31
GABRP O00591 1/20 0.31
GABRD O14764 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1637046 0.82 TPMT (0.34) TPMTHCAR1SMN1; SMN2
SCHEMBL11534820 0.80 PARP1 (0.36) TPMTKDM4E
SCHEMBL7491792 0.75 TPMT (0.39) TPMTHCAR1KDM4EKMT2ARXRA
SCHEMBL1636895 0.73
Benzene SCHEMBL8022186 0.72 ACHE (0.37) TPMTALDH1A1SELLSELPSELE
SCHEMBL18896 0.71
SCHEMBL5052149 0.69 TPMT (0.56) TPMTHCAR1KDM4ERXRARXRB
SCHEMBL23531515 0.68 ALDH1A1 (0.37) ALDH1A1SELLSELPSELE
SCHEMBL9982849 0.68 ALDH1A1 (0.37) ALDH1A1SELLSELPSELE
SCHEMBL669285 0.68 ALDH1A1 (0.37) ALDH1A1SELLSELPSELE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112778125-B Aryl phenol compound and synthesis method and application thereof 华东师范大学 2023-02-17 CN claimed
CN-112778125-A Aryl phenol compound and synthesis method and application thereof 华东师范大学 2021-05-11 CN claimed
CN-112778125-B Aryl phenol compound and synthesis method and application thereof 华东师范大学 2023-02-17 CN disclosed
CN-112778125-A Aryl phenol compound and synthesis method and application thereof 华东师范大学 2021-05-11 CN disclosed