Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 12/20 | 0.49 |
| ▸ | NMBR | P28336 | 1/20 | 0.47 |
| ▸ | MDM4 | O15151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28913050 | 1.00 | SIRT2 (0.49) | SIRT2NMBRMDM4TP53 | |
| SCHEMBL29399601 | 1.00 | SIRT2 (0.49) | SIRT2NMBRMDM4TP53 | |
| SCHEMBL30468161 | 0.92 | SIRT2 (0.55) | SIRT2NMBRMDM4TP53 | |
| SCHEMBL29670271 | 0.89 | MDM4 (0.49) | SIRT2NMBRMDM4TP53 | |
| SCHEMBL29368020 | 0.88 | MDM4 (0.54) | SIRT2MDM4TP53 | |
| SCHEMBL1737899 | 0.88 | MDM4 (0.54) | SIRT2MDM4TP53 | |
| SCHEMBL30433831 | 0.88 | MDM4 (0.54) | SIRT2MDM4TP53 | |
| SCHEMBL12994493 | 0.88 | MDM4 (0.54) | SIRT2MDM4TP53 | |
| SCHEMBL13227674 | 0.88 | MDM4 (0.54) | SIRT2MDM4TP53 | |
| SCHEMBL30385679 | 0.88 | MDM4 (0.49) | SIRT2NMBRMDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112851536-B | Method for constructing amide bond by clicking pyrimidine condensing agent and application of method in amide and polypeptide synthesis | 兰州大学 | 2022-02-25 | — | — | CN | disclosed |
| CN-112851536-A | Method for constructing amide bond by clicking pyrimidine condensing agent and application of method in amide and polypeptide synthesis | 兰州大学 | 2021-05-28 | — | — | CN | disclosed |