SCHEMBL2891328

SCHEMBL2891328

C=C(C)C(=O)N[C@@H](CS)C(=O)OC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MAPT P10636 1/20 0.41
THRB P10828 1/20 0.41
ALOX15 P16050 1/20 0.41
NFKB1 P19838 1/20 0.41
PTGS2 P35354 1/20 0.41
THPO P40225 1/20 0.41
RECQL P46063 1/20 0.41
BLM P54132 1/20 0.41
ALDH1A1 P00352 1/20 0.35
ACE P12821 1/20 0.34
TSHR P16473 2/20 0.33
HSD17B10 Q99714 1/20 0.31
TAS1R3 Q7RTX0 2/20 0.31
TAS1R1 Q7RTX1 2/20 0.31
FNTA P49354 1/20 0.31
FNTB P49356 1/20 0.31
ITGB1 P05556 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4984084 0.86 SMN1; SMN2 (0.43) TGFBR1SMN1; SMN2KDM4EMAPTTHRB
SCHEMBL10505071 0.86 SMN1; SMN2 (0.43) TGFBR1SMN1; SMN2KDM4EMAPTTHRB
SCHEMBL29716049 0.81 TGFBR1 (0.50) TGFBR1ALDH1A1TSHRITGB1ITGA4
SCHEMBL9985663 0.81 TGFBR1 (0.69) TGFBR1SMN1; SMN2KDM4EMAPTTHRB
SCHEMBL9984709 0.81 TGFBR1 (0.69) TGFBR1SMN1; SMN2KDM4EMAPTTHRB
SCHEMBL112331 0.80 SMN1; SMN2 (0.63) SMN1; SMN2KDM4EMAPTTHRBALOX15
SCHEMBL14088106 0.80 SMN1; SMN2 (0.63) SMN1; SMN2KDM4EMAPTTHRBALOX15
SCHEMBL112332 0.80 SMN1; SMN2 (0.63) SMN1; SMN2KDM4EMAPTTHRBALOX15
SCHEMBL7098405 0.80 TAS1R3 (0.49) TGFBR1SMN1; SMN2ALDH1A1TAS1R3TAS1R1
SCHEMBL8955981 0.80 TGFBR1 (0.49) TGFBR1ALDH1A1TSHRHSD17B10TAS1R3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4737561-A2 PROCESSES FOR GENERATING ENGINEERED CELLS AND COMPOSITIONS THEREOF Juno Therapeutics, Inc. (US) 2026-05-06 EP disclosed
EP-4051402-B1 CELL SELECTION AND/OR STIMULATION DEVICES AND METHODS OF USE C3S2 GMBH (DE) 2026-04-29 EP disclosed
US-20260078165-A1 PROCESSES FOR GENERATING ENGINEERED CELLS AND COMPOSITIONS THEREOF JUNO THERAPEUTICS, INC. (US) 2026-03-19 US disclosed
US-12522660-B2 Methods for selection and stimulation of cells and apparatus for same C3S2 GMBH (DE) 2026-01-13 US disclosed
US-12516099-B2 Processes for generating engineered cells and compositions thereof JUNO THERAPEUTICS, INC. (US) 2026-01-06 US disclosed
EP-4658675-A1 METHODS FOR NON-VIRAL MANUFACTURING OF ENGINEERED IMMUNE CELLS C3S2 GmbH (DE) 2025-12-10 EP disclosed
EP-4647493-A2 OLIGOMERIC PARTICLE REAGENTS AND METHODS OF USE THEREOF Juno Therapeutics, Inc. (US) 2025-11-12 EP disclosed
US-20250297282-A1 VIRAL-BINDING PROTEIN AND RELATED REAGENTS, ARTICLES, AND METHODS OF USE JUNO THERAPEUTICS GMBH (DE) 2025-09-25 US disclosed
EP-4615960-A1 METHODS FOR MANUFACTURING ENGINEERED IMMUNE CELLS C3S2 GmbH (DE) 2025-09-17 EP disclosed
US-20250283037-A1 METHODS FOR STIMULATING AND TRANSDUCING T CELLS JUNO THERAPEUTICS GMBH (DE) 2025-09-11 US disclosed
US-20140234873-A1 APPARATUS FOR PROCESSING A SAMPLE IN A LIQUID DROPLET AND METHOD OF USING THE SAME AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2014-08-21 US disclosed
WO-2013124474-A2 CHROMATOGRAPHIC ISOLATION OF CELLS AND OTHER COMPLEX BIOLOGICAL MATERIALS STAGE CELL THERAPEUTICS GMBH (DE) 2013-08-29 WO disclosed
US-8216855-B2 Method of processing a biological and/or chemical sample AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2012-07-10 US disclosed
US-20100285573-A1 Apparatus for processing a sample in a liquid droplet and method of using the same AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2010-11-11 US disclosed
US-20090289213-A1 METHOD OF PROCESSING A BIOLOGICAL AND/OR CHEMICAL SAMPLE AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2009-11-26 US disclosed
EP-2102650-A1 APPARATUS FOR PROCESSING A SAMPLE IN A LIQUID DROPLET AND METHOD OF USING THE SAME Agency for Science, Technology And Research (SG) 2009-09-23 EP disclosed
EP-1989529-A1 METHOD OF PROCESSING A BIOLOGICAL AND/OR CHEMICAL SAMPLE Agency for Science, Technology and Research (SG) 2008-11-12 EP disclosed
WO-2008063135-A1 APPARATUS FOR PROCESSING A SAMPLE IN A LIQUID DROPLET AND METHOD OF USING THE SAME AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2008-05-29 WO disclosed
WO-2008063136-A1 APPARATUS FOR PROCESSING A SAMPLE IN A LIQUID DROPLET AND METHOD OF USING THE SAME AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2008-05-29 WO disclosed
WO-2007094739-A1 METHOD OF PROCESSING A BIOLOGICAL AND/OR CHEMICAL SAMPLE AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2007-08-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078165-A1 PROCESSES FOR GENERATING ENGINEERED CELLS AND COMPOSITIONS THEREOF CD4, CD69, ICOS TGFBR1 1255/4885SMN1; SMN2 379/4885KDM4E 4881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.