Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10505071 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2THRBKDM4EMAPTALOX15 | |
| SCHEMBL10951417 | 0.88 | TGFBR1 (0.46) | SMN1; SMN2THRBKDM4EMAPTALOX15 | |
| SCHEMBL10503056 | 0.87 | HDAC1 (0.37) | SMN1; SMN2THRBKDM4EMAPTALOX15 | |
| SCHEMBL2891328 | 0.86 | TGFBR1 (0.50) | SMN1; SMN2THRBKDM4EMAPTALOX15 | |
| SCHEMBL7924715 | 0.84 | SMN1; SMN2 (0.42) | SMN1; SMN2THRBKDM4EMAPTALOX15 | |
| SCHEMBL14088106 | 0.84 | SMN1; SMN2 (0.63) | SMN1; SMN2THRBKDM4EMAPTALOX15 | |
| SCHEMBL112331 | 0.84 | SMN1; SMN2 (0.63) | SMN1; SMN2THRBKDM4EMAPTALOX15 | |
| SCHEMBL1762251 | 0.84 | THRB (0.47) | SMN1; SMN2THRBKDM4EMAPTALOX15 | |
| SCHEMBL112332 | 0.84 | SMN1; SMN2 (0.63) | SMN1; SMN2THRBKDM4EMAPTALOX15 | |
| SCHEMBL5056684 | 0.84 | SMN1; SMN2 (0.42) | SMN1; SMN2THRBKDM4EMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080138309-A1 | Use Of Aminodithiol As A Reducing Agent For Hair Perming | L'OREAL S.A. (FR) | 2008-06-12 | — | — | US | claimed |
| EP-1844007-A1 | USE OF AMINODITHIOL AS A REDUCING AGENT FOR HAIR PERMING | L'Oréal (FR) | 2007-10-17 | — | — | EP | claimed |
| WO-2006077170-A1 | USE OF AMINODITHIOL AS A REDUCING AGENT FOR HAIR PERMING | L'OREAL (FR) | 2006-07-27 | — | — | WO | claimed |
| US-20080138309-A1 | Use Of Aminodithiol As A Reducing Agent For Hair Perming | L'OREAL S.A. (FR) | 2008-06-12 | — | — | US | disclosed |
| EP-1844007-A1 | USE OF AMINODITHIOL AS A REDUCING AGENT FOR HAIR PERMING | L'Oréal (FR) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006077170-A1 | USE OF AMINODITHIOL AS A REDUCING AGENT FOR HAIR PERMING | L'OREAL (FR) | 2006-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080138309-A1 | Use Of Aminodithiol As A Reducing Agent For Hair Perming | AASDHPPT, BHMT2, ALAD | SMN1; SMN2 4833/4885THRB 3230/4885KDM4E 1902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.