SCHEMBL112331

SCHEMBL112331

COC(=O)C(CS)NC(C)=O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.63
KDM4E B2RXH2 1/20 0.63
MAPT P10636 1/20 0.63
THRB P10828 1/20 0.63
ALOX15 P16050 1/20 0.63
NFKB1 P19838 1/20 0.63
PTGS2 P35354 1/20 0.63
THPO P40225 1/20 0.63
RECQL P46063 1/20 0.63
BLM P54132 1/20 0.63
ALDH1A1 P00352 1/20 0.41
FNTA P49354 1/20 0.40
FNTB P49356 1/20 0.40
ACE P12821 1/20 0.38
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA3 P07451 1/20 0.36
CA4 P22748 1/20 0.36
CA6 P23280 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL112332 1.00 SMN1; SMN2 (0.63) SMN1; SMN2KDM4EMAPTTHRBALOX15
SCHEMBL14088106 1.00 SMN1; SMN2 (0.63) SMN1; SMN2KDM4EMAPTTHRBALOX15
SCHEMBL7999610 0.87 KDM4E (0.63) SMN1; SMN2KDM4EMAPTTHRBALOX15
SCHEMBL5599294 0.87 KDM4E (0.63) SMN1; SMN2KDM4EMAPTTHRBALOX15
SCHEMBL2298043 0.87 KDM4E (0.63) SMN1; SMN2KDM4EMAPTTHRBALOX15
SCHEMBL7999598 0.87 KDM4E (0.63) SMN1; SMN2KDM4EMAPTTHRBALOX15
SCHEMBL23870628 0.85 KDM4E (0.61) SMN1; SMN2KDM4EMAPTTHRBALOX15
SCHEMBL6815850 0.85 KDM4E (0.61) SMN1; SMN2KDM4EMAPTTHRBALOX15
SCHEMBL7758252 0.85 KDM4E (0.61) SMN1; SMN2KDM4EMAPTTHRBALOX15
SCHEMBL4984084 0.84 SMN1; SMN2 (0.43) SMN1; SMN2KDM4EMAPTTHRBALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 333 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4626414-A1 SYNERGISTIC COMBINATIONS OF REGULATED NECROSIS INHIBITORS WITH N-ACETYLCYSTEINE Seabelife (FR) 2025-10-08 EP claimed
US-12435294-B2 Prevention of the oxidation of perfumery raw materials and food raw materials FIRMENICH SA (CH) 2025-10-07 US claimed
CN-118515869-A Polysulfide polymer, preparation method and application thereof 四川大学 2024-08-20 CN claimed
WO-2024115793-A1 SYNERGISTIC COMBINATIONS OF REGULATED NECROSIS INHIBITORS WITH N-ACETYLCYSTEINE SEABELIFE (FR) 2024-06-06 WO claimed
US-20230210735-A1 PREVENTION, REDUCTION, OR AMELIORATION OF OLD PERSON SMELL FIRMENICH SA (CH) 2023-07-06 US claimed
EP-4164587-A1 PREVENTION, REDUCTION, OR AMELIORATION OF OLD PERSON SMELL Firmenich SA (CH) 2023-04-19 EP claimed
US-20220409526-A1 COMPOUNDS AND IMPLANTS FOR TREATING OCULAR DISORDERS RETINA FOUND OF THE SOUTHWEST (US) 2022-12-29 US claimed
US-20210395638-A1 PREVENTION OF THE OXIDATION OF PERFUMERY RAW MATERIALS AND FOOD RAW MATERIALS FIRMENICH SA (CH) 2021-12-23 US claimed
WO-2021250130-A1 PREVENTION, REDUCTION, OR AMELIORATION OF OLD PERSON SMELL FIRMENICH SA (CH) 2021-12-16 WO claimed
EP-3856358-A2 PREVENTION OF THE OXIDATION OF PERFUMERY RAW MATERIALS AND FOOD RAW MATERIALS Firmenich SA (CH) 2021-08-04 EP claimed
WO-2021127642-A1 SELECTIVE VALORIZATION OF BIOMASS SUGARS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2021-06-24 WO claimed
CN-109651503-A A kind of preparation method and application of artificial antigen 天津国际生物医药联合研究院 2019-04-19 CN claimed
US-8575382-B2 Low molecular weight pharmacological activity modulators “Ivy Pharm” LLC (RU) 2013-11-05 US claimed
CN-102802605-A Stable lipid formulations of apoptosis promoters ABBOTT LAB 2012-11-28 CN claimed
US-20120202764-A1 LOW MOLECULAR WEIGHT PHARMACOLOGICAL ACTIVITY MODULATORS "IVY PHARM" JSC. (RU) 2012-08-09 US claimed
EP-2455386-A1 LOW MOLECULAR WEIGHT PHARMACOLOGICAL ACTIVITY MODULATORS "Ivy Pharm" Jsc. (RU) 2012-05-23 EP claimed
EP-2424499-A1 STABILIZED LIPID FORMULATION OF APOPTOSIS PROMOTER Abbott Laboratories (US) 2012-03-07 EP claimed
WO-2010127193-A1 STABILIZED LIPID FORMULATION OF APOPTOSIS PROMOTER ABBOTT LABORATORIES (US) 2010-11-04 WO claimed
US-20100278905-A1 STABILIZED LIPID FORMULATION OF APOPTOSIS PROMOTER ABBVIE INC. 2010-11-04 US claimed
US-RE41339-E1 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use TRISTRATA, INC. (US) 2010-05-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120202764-A1 LOW MOLECULAR WEIGHT PHARMACOLOGICAL ACTIVITY MODULATORS OPRM1, SIGMAR1, TACR1 SMN1; SMN2 3480/4885KDM4E 4082/4885MAPT 3722/4885
US-20220409526-A1 COMPOUNDS AND IMPLANTS FOR TREATING OCULAR DISORDERS PDE6C, STRA6, PDE6A SMN1; SMN2 2532/4885KDM4E 3217/4885MAPT 2605/4885
US-12435294-B2 Prevention of the oxidation of perfumery raw materials and food raw materials CUTA, MPO, GPX4 SMN1; SMN2 2584/4885KDM4E 4695/4885MAPT 3913/4885
US-20230210735-A1 PREVENTION, REDUCTION, OR AMELIORATION OF OLD PERSON SMELL ACHE, RBP4, LPO SMN1; SMN2 421/4885KDM4E 3481/4885MAPT 2985/4885
US-20210395638-A1 PREVENTION OF THE OXIDATION OF PERFUMERY RAW MATERIALS AND FOOD RAW MATERIALS CUTA, MPO, GPX4 SMN1; SMN2 2584/4885KDM4E 4695/4885MAPT 3913/4885
US-20100278905-A1 STABILIZED LIPID FORMULATION OF APOPTOSIS PROMOTER BCL2, BAX, BCOR SMN1; SMN2 820/4885KDM4E 3045/4885MAPT 3440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.