Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | AGXT | P21549 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28914545 | 0.89 | TAAR1 (0.52) | TAAR1OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL30063439 | 0.89 | TAAR1 (0.52) | TAAR1OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL613450 | 0.84 | TAAR1 (0.47) | TAAR1OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL5672427 | 0.80 | OPRM1 (0.55) | OPRM1OPRL1OPRD1OPRK1TDP1 | |
| SCHEMBL5495685 | 0.74 | DPP4 (0.39) | OPRM1OPRL1 | |
| SCHEMBL5499282 | 0.74 | SIGMAR1 (0.51) | TAAR1 | |
| SCHEMBL5175182 | 0.71 | OPRM1 (0.56) | OPRM1OPRL1OPRD1OPRK1SMN1; SMN2 | |
| SCHEMBL5237164 | 0.71 | OPRM1 (0.39) | TAAR1OPRM1OPRL1 | |
| SCHEMBL26478943 | 0.71 | L3MBTL1 (0.43) | OPRM1OPRD1SMN1; SMN2TDP1 | |
| SCHEMBL5500258 | 0.71 | SIGMAR1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104837817-A | New synthetic route for preparation of 3-amino-piperidine compounds | LEK PHARMACEUTICALS | 2015-08-12 | — | — | CN | disclosed |