Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | ECE1 | P42892 | 10/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28582778 | 0.86 | CCR2 (0.48) | NR1I2F10KDM4ECMA1ALDH1A1 | |
| SCHEMBL21822200 | 0.84 | CCR9 (0.42) | ROCK1F10KDM4ECMA1ALDH1A1 | |
| SCHEMBL21822205 | 0.84 | F10 (0.51) | F10 | |
| SCHEMBL28598807 | 0.79 | F10 (0.42) | F10ECE1 | |
| SCHEMBL28593853 | 0.78 | HTR6 (0.44) | F10ECE1 | |
| SCHEMBL25015959 | 0.77 | F10 (0.44) | ROCK1F10ECE1 | |
| SCHEMBL25017551 | 0.77 | F10 (0.48) | ROCK1F10 | |
| SCHEMBL28582801 | 0.76 | CCR2 (0.42) | F10KMT2A | |
| SCHEMBL28916214 | 0.74 | NQO2 (0.48) | F10KDM4ECMA1MAPTHTT | |
| SCHEMBL25015803 | 0.73 | F10 (0.52) | F10ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996529-A | Matriptase 2 inhibitor and application thereof | 迪斯克医药公司 | 2021-06-18 | — | — | CN | disclosed |