Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11515966 | 0.75 | MAOA (0.41) | BCHEPPARGPOLBMAOASMN1; SMN2 | |
| SCHEMBL28584671 | 0.72 | PPARG (0.42) | PPARGMAPTPOLBMAOASMN1; SMN2 | |
| SCHEMBL7611171 | 0.67 | BCHE (0.56) | BCHEMAPTPOLBMAOASMN1; SMN2 | |
| SCHEMBL7992802 | 0.66 | MAOA (0.42) | PPARGMAPTPOLBMAOASMN1; SMN2 | |
| SCHEMBL8525463 | 0.65 | PPARG (0.39) | BCHEPPARGPOLBALDH1A1TSHR | |
| Hydrogen Sulfide SCHEMBL813627 | 0.64 | PPARG (0.38) | BCHEPPARGPOLBALDH1A1TSHR | |
| SCHEMBL5806333 | 0.63 | MAOA (0.39) | PPARGPOLBMAOASMN1; SMN2ALDH1A1 | |
| SCHEMBL28704042 | 0.63 | BCHE (0.39) | BCHEMAOASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7528727 | 0.62 | SMN1; SMN2 (0.46) | PPARGMAPTSMN1; SMN2ALDH1A1TSHR | |
| Hydrogen Sulfide SCHEMBL7021865 | 0.62 | PPARG (0.39) | BCHEPPARGPOLBSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113024483-A | Preparation method of 2-substituted benzothiazole derivative | 无锡鸣鹭医药科技有限公司 | 2021-06-25 | — | — | CN | claimed |
| CN-113024483-A | Preparation method of 2-substituted benzothiazole derivative | 无锡鸣鹭医药科技有限公司 | 2021-06-25 | — | — | CN | disclosed |