Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992802 | 0.86 | MAOA (0.42) | MAOAPPARGSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL5806333 | 0.83 | MAOA (0.39) | MAOAPPARGSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL11515393 | 0.79 | MAOA (0.36) | MAOAPPARGSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL28584671 | 0.78 | PPARG (0.42) | MAOAPPARGSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL10358772 | 0.76 | ALDH1A1 (0.35) | MAOAPPARGSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL12264201 | 0.75 | MAOA (0.46) | MAOASMN1; SMN2ALDH1A1KDM1AADRA2A | |
| SCHEMBL28916911 | 0.75 | BCHE (0.37) | MAOAPPARGSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL18434891 | 0.75 | MEN1 (0.36) | MAOAPPARGSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL9505193 | 0.74 | SMN1; SMN2 (0.34) | MAOAPPARGSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL16728889 | 0.74 | MAOA (0.45) | MAOASMN1; SMN2ALDH1A1TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3725775-A1 | PYRIDINE- AND PYRIMIDINECARBOXAMIDES AS CXCR2 MODULATORS | Syntrix Biosystems, Inc. (US) | 2020-10-21 | — | — | EP | disclosed |
| US-4145537-A | BENZOTHIAZOLIUM DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-03-20 | — | — | US | disclosed |