Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992802 | 0.85 | MAOA (0.42) | MAOAADRA2AADRA2BADRA2CCHRM3 | |
| SCHEMBL11515966 | 0.83 | MAOA (0.41) | MAOAADRA2AADRA2BADRA2CCHRM3 | |
| SCHEMBL10358772 | 0.78 | ALDH1A1 (0.35) | MAOAMEN1KMT2APPARGALDH1A1 | |
| SCHEMBL11515393 | 0.77 | MAOA (0.36) | MAOAADRA2AADRA2BADRA2CCHRM3 | |
| SCHEMBL31571121 | 0.75 | MAOA (0.43) | MAOAPIM1ADRA2AADRA2BADRA2C | |
| SCHEMBL8931214 | 0.75 | MAOA (0.43) | MAOAPIM1ADRA2AADRA2BADRA2C | |
| SCHEMBL12264201 | 0.74 | MAOA (0.46) | MAOAADRA2AADRA2BADRA2CCHRM3 | |
| SCHEMBL18434891 | 0.74 | MEN1 (0.36) | MAOAMEN1KMT2AKDM1APPARG | |
| SCHEMBL9505193 | 0.73 | SMN1; SMN2 (0.34) | MAOAMEN1KMT2APPARGALDH1A1 | |
| SCHEMBL16728889 | 0.72 | MAOA (0.45) | MAOAADRA2AADRA2BADRA2CCHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006102987-A1 | AGENTS FOR COLOURING FIBRES CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-10-05 | — | — | WO | disclosed |