Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28590708 | 0.87 | NPC1 (0.35) | L3MBTL1NPC1RAB9AGAAHPGD | |
| SCHEMBL28916717 | 0.81 | SMN1; SMN2 (0.33) | L3MBTL1NPC1RAB9AGAAHPGD | |
| SCHEMBL28595287 | 0.79 | HTR6 (0.39) | NPC1RAB9A | |
| SCHEMBL28595291 | 0.79 | HTR6 (0.39) | NPC1RAB9A | |
| SCHEMBL4354349 | 0.75 | L3MBTL1 (0.36) | L3MBTL1NPC1RAB9AGAAALDH1A1 | |
| SCHEMBL4354359 | 0.75 | CYP3A4 (0.37) | L3MBTL1RAB9AGAAALDH1A1USP2 | |
| SCHEMBL28916708 | 0.74 | NAMPT (0.36) | LMNAPOLB | |
| SCHEMBL28584238 | 0.71 | L3MBTL1 (0.36) | L3MBTL1NPC1RAB9AGAAHPGD | |
| SCHEMBL1536043 | 0.70 | ALDH1A1 (0.41) | L3MBTL1NPC1RAB9AGAAHPGD | |
| SCHEMBL1536171 | 0.70 | L3MBTL1 (0.50) | L3MBTL1GAAHPGDALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053742-B | Novel tricyclic compounds | ABBVIE 公司 | 2021-06-15 | — | — | CN | disclosed |