Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 2/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SPR | P35270 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 7/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4377009 | 0.81 | MTNR1A (0.41) | HTR1DHTR1BTSHRSPRTACR1 | |
| SCHEMBL17066884 | 0.76 | HTR1D (0.55) | HTR1DHTR1BHTR1ANFKB1HTR2A | |
| SCHEMBL29026421 | 0.75 | GSK3B (0.42) | — | |
| SCHEMBL4500910 | 0.72 | MTNR1A (0.62) | TSHRCYP3A4MAPTALOX15HTR2A | |
| SCHEMBL26086383 | 0.71 | STING1 (0.44) | TSHRKDM4E | |
| SCHEMBL18854105 | 0.70 | HTR1D (0.51) | HTR1DHTR1BHTR1ANFKB1HTR2A | |
| SCHEMBL20921203 | 0.69 | TSHR (0.64) | HTR1DHTR1BTSHRSPRBLM | |
| SCHEMBL29190382 | 0.68 | MTNR1A (0.40) | TSHRNPSR1KDM4EALDH1A1LMNA | |
| SCHEMBL14555321 | 0.68 | ATM (0.47) | HTR1DHTR1BHTR1ANFKB1HTR2A | |
| SCHEMBL7449324 | 0.68 | HTR2A (0.70) | HTR1DHTR1BTSHRBLMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115348957-A | Compounds and compositions for treating diseases associated with STING activity | 艾福姆德尤股份有限公司 | 2022-11-15 | — | — | CN | disclosed |