Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CCKBR | P32239 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31228282 | 0.78 | MTNR1A (0.36) | MTNR1AMTNR1B | |
| SCHEMBL25896801 | 0.74 | MTNR1A (0.49) | MTNR1AMTNR1BCYP2D6CYP1A2CYP3A4 | |
| SCHEMBL5346251 | 0.72 | MTNR1A (0.73) | MTNR1AMTNR1BCYP2D6CYP2C19CYP1A2 | |
| SCHEMBL4377009 | 0.70 | MTNR1A (0.41) | MTNR1AMTNR1BCYP2D6CYP2C19CYP1A2 | |
| SCHEMBL26658318 | 0.70 | STING1 (0.34) | MTNR1AMTNR1BADORA2AHTR1F | |
| SCHEMBL30390687 | 0.70 | STING1 (0.34) | MTNR1AMTNR1BADORA2AHTR1F | |
| SCHEMBL28918253 | 0.68 | HTR1D (0.42) | MTNR1AMTNR1BCYP3A4TSHRKDM4E | |
| SCHEMBL31228568 | 0.68 | MTNR1A (0.30) | MTNR1AMTNR1B | |
| SCHEMBL23195348 | 0.68 | F7 (0.44) | CYP1A2ADORA2AKDM4EHPGD | |
| SCHEMBL29592699 | 0.68 | F7 (0.44) | CYP1A2ADORA2AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116261452-A | Compounds and compositions for the treatment of diseases associated with STING activity | 艾福姆德尤股份有限公司 | 2023-06-13 | — | — | CN | disclosed |