Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | MGAM | O43451 | 3/20 | 0.45 |
| ▸ | SI | P14410 | 3/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | CA9 | Q16790 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6226548 | 0.91 | GPR35 (0.49) | GAAMGAMSIMGAM2GPR35 | |
| SCHEMBL3281348 | 0.77 | MAOB (0.50) | GAAMGAMSIMGAM2MAOB | |
| SCHEMBL6679976 | 0.77 | GAA (0.44) | GAAMGAMSIMGAM2MAOB | |
| SCHEMBL7025063 | 0.77 | CA12 (0.47) | GAAGPR35ALDH1A1HPGDCA9 | |
| SCHEMBL10602195 | 0.75 | GAA (0.46) | GAAMGAMSIMGAM2MAOB | |
| SCHEMBL1561361 | 0.74 | GAA (0.53) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL14199261 | 0.74 | MAOB (0.53) | GAAMGAMSIMGAM2MAOB | |
| SCHEMBL28918554 | 0.71 | GAA (0.50) | GAAMGAMSIMGAM2GPR35 | |
| SCHEMBL28728668 | 0.70 | CA9 (0.59) | GAAMAOBALDH1A1HPGDCA9 | |
| SCHEMBL8199017 | 0.68 | GPR35 (0.55) | GPR35MAOBALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115368333-A | Compound containing ibuprofen-coumarin skeleton and application thereof | 湖北医药学院 | 2022-11-22 | — | — | CN | disclosed |