Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | RORC | P51449 | 2/20 | 0.46 |
| ▸ | RARG | P13631 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2953334 | 0.85 | ALDH1A1 (0.56) | CNR1LMNATHRBGAAALDH1A1 | |
| SCHEMBL28919074 | 0.85 | PKM (0.62) | GAAALDH1A1MAPTTSHRPOLB | |
| SCHEMBL29043230 | 0.84 | MAPT (0.55) | CNR1LMNATHRBGAAALDH1A1 | |
| SCHEMBL28919025 | 0.84 | NR1H4 (0.58) | CNR1NR1H4LMNAGAAALDH1A1 | |
| SCHEMBL30080500 | 0.84 | NR1H4 (0.58) | CNR1NR1H4LMNAGAAALDH1A1 | |
| SCHEMBL28919065 | 0.83 | POLB (0.61) | CNR1LMNATSHRPOLBATM | |
| SCHEMBL28919053 | 0.81 | MAPT (0.61) | LMNATHRBALDH1A1MAPTPOLB | |
| SCHEMBL10901539 | 0.81 | GCK (0.61) | LMNAGAAALDH1A1MAPTTSHR | |
| SCHEMBL28919079 | 0.81 | CNR1 (0.51) | CNR1LMNAALDH1A1TSHRPOLB | |
| SCHEMBL10901819 | 0.81 | HSD11B1 (0.64) | LMNATHRBGAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521272-B | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2023-07-21 | — | — | CN | disclosed |
| CN-115521272-A | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2022-12-27 | — | — | CN | disclosed |