Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | CNR1 | P21554 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MET | P08581 | 5/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28919016 | 0.85 | PKLR (0.65) | POLBLMNACASP6MEN1KMT2A | |
| SCHEMBL28919051 | 0.84 | POLB (0.56) | POLBCNR1LMNAATMMEN1 | |
| SCHEMBL28919039 | 0.83 | CNR1 (0.53) | POLBCNR1LMNAATMMEN1 | |
| SCHEMBL28919066 | 0.83 | CNR1 (0.57) | POLBCNR1LMNAATMMEN1 | |
| SCHEMBL30080684 | 0.82 | POLB (0.60) | POLBCNR1ATMMEN1KMT2A | |
| SCHEMBL28919079 | 0.81 | CNR1 (0.51) | POLBCNR1LMNAATMMEN1 | |
| SCHEMBL28919025 | 0.78 | NR1H4 (0.58) | POLBCNR1LMNAATMMEN1 | |
| SCHEMBL30080500 | 0.78 | NR1H4 (0.58) | POLBCNR1LMNAATMMEN1 | |
| SCHEMBL28919081 | 0.78 | KMT2A (0.54) | POLBCNR1ATMMEN1KMT2A | |
| SCHEMBL18711450 | 0.78 | CNR1 (0.68) | POLBCNR1ATMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521272-B | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2023-07-21 | — | — | CN | disclosed |
| CN-115521272-A | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2022-12-27 | — | — | CN | disclosed |