Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28961516 | 0.88 | ALDH1A1 (0.66) | ALDH1A1NPSR1TSHRHTTESR1 | |
| SCHEMBL28919157 | 0.86 | POLB (0.58) | ALDH1A1NPSR1TSHRHTTKMT2A | |
| SCHEMBL28919160 | 0.84 | POLB (0.53) | ALDH1A1KMT2AL3MBTL1POLBKDM4E | |
| SCHEMBL29043226 | 0.78 | KMT2A (0.56) | ALDH1A1TSHRHTTKMT2APOLB | |
| SCHEMBL6582577 | 0.77 | ALDH1A1 (0.88) | ALDH1A1NPSR1TSHRHTTKMT2A | |
| SCHEMBL1834666 | 0.75 | ALDH1A1 (0.84) | ALDH1A1NPSR1TSHRHTTKMT2A | |
| SCHEMBL28919050 | 0.74 | HTT (0.54) | ALDH1A1NPSR1HTTKMT2APOLB | |
| SCHEMBL28919079 | 0.74 | CNR1 (0.51) | ALDH1A1TSHRKMT2APOLBKDM4E | |
| SCHEMBL27834699 | 0.70 | ALDH1A1 (0.74) | ALDH1A1NPSR1TSHRHTTKMT2A | |
| SCHEMBL346982 | 0.70 | ALDH1A1 (0.74) | ALDH1A1NPSR1TSHRHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521272-B | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2023-07-21 | — | — | CN | disclosed |
| CN-115521272-A | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2022-12-27 | — | — | CN | disclosed |