Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28919157 | 0.91 | POLB (0.58) | KMT2APOLBALDH1A1TSHRHTT | |
| SCHEMBL28919028 | 0.88 | PKM (0.51) | KMT2APOLBALDH1A1HTTTDP1 | |
| SCHEMBL28919081 | 0.82 | KMT2A (0.54) | KMT2APOLBNR1H4MEN1CNR1 | |
| SCHEMBL28919079 | 0.78 | CNR1 (0.51) | KMT2APOLBALDH1A1TSHRMEN1 | |
| SCHEMBL28919050 | 0.78 | HTT (0.54) | KMT2APOLBALDH1A1HTTTDP1 | |
| SCHEMBL28919048 | 0.78 | ALDH1A1 (0.67) | KMT2APOLBALDH1A1TSHRHTT | |
| SCHEMBL21198678 | 0.76 | HTT (0.56) | KMT2APOLBALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL28919023 | 0.75 | CNR1 (0.45) | KMT2APOLBNR1H4MEN1CNR1 | |
| SCHEMBL21202227 | 0.75 | HTT (0.55) | KMT2APOLBALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL28919078 | 0.73 | MEN1 (0.43) | KMT2APOLBNR1H4MEN1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521272-B | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2023-07-21 | — | — | CN | disclosed |