Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29043226 | 0.91 | KMT2A (0.56) | POLBKMT2AHTTNR1H4CNR1 | |
| SCHEMBL28919050 | 0.87 | HTT (0.54) | POLBKMT2AHTTALDH1A1NPSR1 | |
| SCHEMBL28919048 | 0.86 | ALDH1A1 (0.67) | POLBKMT2AHTTCNR1ALDH1A1 | |
| SCHEMBL28919079 | 0.83 | CNR1 (0.51) | POLBKMT2ACNR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28919028 | 0.78 | PKM (0.51) | POLBKMT2AHTTALDH1A1TDP1 | |
| SCHEMBL28919081 | 0.75 | KMT2A (0.54) | POLBKMT2ANR1H4CNR1 | |
| SCHEMBL546627 | 0.74 | HTT (0.77) | POLBHTTALDH1A1NPSR1KDM4E | |
| SCHEMBL28961516 | 0.74 | ALDH1A1 (0.66) | POLBHTTALDH1A1NPSR1TSHR | |
| SCHEMBL28919160 | 0.74 | POLB (0.53) | POLBKMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL3823611 | 0.74 | HTT (0.70) | POLBKMT2AHTTALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521272-B | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2023-07-21 | — | — | CN | disclosed |
| CN-115521272-A | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2022-12-27 | — | — | CN | disclosed |