Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKLR | P30613 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 5/20 | 0.56 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28919051 | 0.86 | POLB (0.56) | POLBMEN1KMT2ALMNAGLA | |
| SCHEMBL28919016 | 0.85 | PKLR (0.65) | PKLRPOLBPKMMEN1KMT2A | |
| SCHEMBL8658563 | 0.78 | HPGD (0.68) | POLBPKMKMT2ALMNAALDH1A1 | |
| SCHEMBL17800942 | 0.76 | PKM (0.74) | PKLRPOLBPKMLMNAHTT | |
| SCHEMBL2239830 | 0.75 | PKM (1.00) | PKLRPOLBPKM | |
| SCHEMBL7069343 | 0.75 | F10 (0.61) | PKMLMNAHTTGLAALDH1A1 | |
| SCHEMBL30080386 | 0.74 | PKM (0.72) | PKLRPOLBPKMLMNAHTT | |
| SCHEMBL30080582 | 0.73 | PKM (0.60) | PKLRPOLBPKMMEN1KMT2A | |
| SCHEMBL17808941 | 0.73 | PKM (0.60) | PKLRPOLBPKMALDH1A1 | |
| SCHEMBL28919041 | 0.73 | KMT2A (0.60) | PKLRPOLBPKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521272-A | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2022-12-27 | — | — | CN | disclosed |