Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.60 |
| ▸ | PKLR | P30613 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30080684 | 0.85 | POLB (0.60) | MEN1KMT2AKDM4EPOLBALDH1A1 | |
| SCHEMBL30080392 | 0.84 | PKM (0.60) | PKMPKLRKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL28919016 | 0.83 | PKLR (0.65) | PKMPKLRMEN1KMT2AHTT | |
| SCHEMBL17800942 | 0.82 | PKM (0.74) | PKMPKLRHTTPOLBLMNA | |
| SCHEMBL16026538 | 0.78 | ALDH1A1 (0.79) | MEN1KMT2AHTTTSHRSMN1; SMN2 | |
| SCHEMBL2239830 | 0.78 | PKM (1.00) | PKMPKLRPOLB | |
| SCHEMBL30080386 | 0.77 | PKM (0.72) | PKMPKLRHTTPOLBLMNA | |
| SCHEMBL14778164 | 0.77 | PKLR (0.51) | PKMPKLRMEN1KMT2AKDM4E | |
| SCHEMBL19871301 | 0.75 | PKM (0.79) | PKMPKLRPOLBLMNAALDH1A1 | |
| SCHEMBL28919059 | 0.73 | PKLR (0.60) | PKMPKLRMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521272-A | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2022-12-27 | — | — | CN | disclosed |