Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28919072 | 0.87 | PKM (0.55) | CNR1ALDH1A1TSHRGAAPKM | |
| SCHEMBL28919079 | 0.84 | CNR1 (0.51) | CNR1ALDH1A1TSHRPOLBKDM4E | |
| SCHEMBL28919065 | 0.83 | POLB (0.61) | CNR1TSHRPOLBLMNAKMT2A | |
| SCHEMBL28919081 | 0.81 | KMT2A (0.54) | CNR1POLBKMT2AMAPK1ATM | |
| SCHEMBL28919039 | 0.78 | CNR1 (0.53) | CNR1ALDH1A1TSHRGAAPOLB | |
| SCHEMBL30080625 | 0.75 | ALDH1A1 (0.55) | CNR1ALDH1A1TSHRGAAPKM | |
| 4-Methylbenzoic Acid SCHEMBL29043235 | 0.74 | CXCR2 (0.48) | CNR1ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL17560192 | 0.74 | SMN1; SMN2 (0.65) | ALDH1A1POLBKDM4EMAPTKMT2A | |
| SCHEMBL30080500 | 0.73 | NR1H4 (0.58) | CNR1ALDH1A1GAAPKMPOLB | |
| SCHEMBL28919025 | 0.73 | NR1H4 (0.58) | CNR1ALDH1A1GAAPKMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521272-B | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2023-07-21 | — | — | CN | disclosed |
| CN-115521272-A | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2022-12-27 | — | — | CN | disclosed |