Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.53 |
| ▸ | EBP | Q15125 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28919079 | 0.89 | CNR1 (0.51) | KMT2AMEN1CNR1POLBMAPK1 | |
| SCHEMBL28919063 | 0.87 | PKM (0.55) | KMT2AMEN1DHCR7EBPSIGMAR1 | |
| SCHEMBL28919023 | 0.85 | CNR1 (0.45) | KMT2AMEN1CNR1POLBKCNH2 | |
| SCHEMBL10898562 | 0.84 | KMT2A (0.64) | KMT2AMEN1POLB | |
| SCHEMBL10899451 | 0.83 | KMT2A (0.75) | KMT2AMEN1DHCR7EBPSIGMAR1 | |
| SCHEMBL29043226 | 0.82 | KMT2A (0.56) | KMT2AMEN1CNR1POLBATM | |
| SCHEMBL28919078 | 0.82 | MEN1 (0.43) | KMT2AMEN1CNR1POLBKCNH2 | |
| SCHEMBL28919066 | 0.81 | CNR1 (0.57) | KMT2AMEN1CNR1POLBMAPK1 | |
| SCHEMBL10898269 | 0.79 | DHCR7 (0.53) | KMT2AMEN1DHCR7EBPSIGMAR1 | |
| SCHEMBL10898676 | 0.79 | KMT2A (0.64) | KMT2AMEN1DHCR7MAPK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521272-B | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2023-07-21 | — | — | CN | disclosed |
| CN-115521272-A | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2022-12-27 | — | — | CN | disclosed |